C13H16N4O
244.29 g/mol
APIWarning
Veliparib
CAS912444-00-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Veliparib is a benzimidazole derivative with a carbamoyl group and a pyrrolidinyl substituent. It is a potent, orally bioavailable inhibitor of poly(ADP-ribose) polymerase (PARP), acting as an EC 2.
PARP inhibitor active pharmaceutical ingredientresearch compound for potentiating DNA-damaging agents in preclinical tumor models
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 912444-00-9
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Safety Reference
Warning
H302Harmful if swallowed
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide
InChIKey
JNAHVYVRKWKWKQ-CYBMUJFWSA-N
SMILES
C[C@@]1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
Synonyms (24)
- Veliparib (JAN/USAN/INN)
- 912444-00-9 (free base)
- ABT-888 (Veliparib)
- ABT888 (free base)?
- PARP-1 INHIBITOR ABT-888
- Veliparib
- Veliparib (ABT-888)
- Veliparib free base
- benzimidazole carboxamide, 3a
- veliparibum