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Home/Compounds/API/Idelalisib
C22H18FN7O
415.4 g/mol
APIDanger

Idelalisib

CAS870281-82-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Idelalisib is a pharmaceutical compound used as an active pharmaceutical ingredient. It is a phosphoinositide 3-kinase inhibitor that blocks the delta isoform of the enzyme, with a structure characterized by multiple aromatic rings and an amine group.

pharmaceutical manufacturing intermediateresearch compound for kinase inhibition studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Health Hazard
Health Hazard
Danger
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H361Suspected of damaging fertility or the unborn child
Identifiers
IUPAC Name

5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one

InChIKey

IFSDAJWBUCMOAH-HNNXBMFYSA-N

SMILES

CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5

Synonyms (33)
  • 40L
  • A-1138
  • CAL-101
  • EX-A330
  • Idelalisib (JAN/USAN/INN)
  • CAL-101 (GS-1101)
  • CAL-101 (Idelalisib)
  • CAL-101 (Idelalisib, GS-1101)
  • CAL-101/CAL101
  • GS 1101
  • GS-1101; Idelalisib; CAL-101
  • GS-11CAL-101
  • Idealisib
  • Idelalisib
  • Idelalisib (CAL-101)
  • Idelalisib (CAL-101,GS-1101)
  • SDCCGSBI-0654408.P001
  • Zydelig
  • Zydelig (TN)
  • idelalisibum