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Home/Compounds/API/Halofuginone
C16H17BrClN3O3
414.7 g/mol
API

Halofuginone

CAS868851-54-1
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Halofuginone is a low molecular weight quinazolinone alkaloid that acts as an inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 gene expression. It is being developed as a pharmaceutical active ingredient for research into fibrotic conditions and cancer metastasis.

pharmaceutical manufacturing intermediateresearch compound for scleroderma studiesresearch compound for tumor progression and metastasis studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Halofuginone hydrobromide

CAS64924-67-0

pharmaceutical raw material

StrongSame Parent

Halofuginone lactate

CAS82186-71-8

pharmaceutical raw material

ReferenceSame Category

Umeclidinium bromide

CAS869113-09-7

pharmaceutical raw material

ReferenceSame Category

Neurokinin B

CAS86933-75-7

pharmaceutical raw material

ReferenceSame Category

Olodaterol hydrochloride

CAS869477-96-3

pharmaceutical raw material

ReferenceSame Category

Tecovirimat

CAS869572-92-9

pharmaceutical raw material

Referencestereoisomer of

(-)-Halofuginone

CAS7695-84-3

pharmaceutical raw material

Identifiers
IUPAC Name

7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one

InChIKey

LVASCWIMLIKXLA-CABCVRRESA-N

SMILES

C1C[C@@H]([C@H](NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O

Synonyms (33)
  • HFG
  • Halofuginona [INN-Spanish]
  • Halofuginonum [INN-Latin]
  • 7-bromo-6-chlorofebrifugine
  • Halocur
  • HalocurTM
  • Halofuginon
  • Halofuginona
  • Halofuginone
  • Halofuginone HCl
  • Halofuginonum
  • Halofunginone
  • halofuginone monohydrobromide