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Home/Compounds/Pharmaceutical Intermediate/(alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-L-phenylalanine
C31H42N4O6
566.7 g/mol
Pharmaceutical Intermediate

L-Phenylalanine, (alphaS)-alpha-((2-(4-morpholinyl)acetyl)amino)benzenebutanoyl-L-leucyl-

CAS868540-16-3EC812-214-9
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected peptide intermediate used in the manufacturing of carfilzomib, a pharmaceutical agent. It features a complex structure containing multiple amide bonds, an aromatic ring system, and a morpholine moiety.

Pharmaceutical intermediate for carfilzomib synthesisResearch compound for peptide-based drug development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.85

(S)-Methyl 2-((S)-4-Methyl-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMido)-3-phenylpropanoate

CAS1140908-89-9

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.82

L-Phenylalanine, (alphaS)-alpha-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-, phenylmethyl ester

CAS875309-92-5

research compound

SimilarStructure SimilarSimilarity 0.78

Carfilzomib

CAS868540-17-4

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.78

(S)-4-Methyl-N-((R)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide

CAS2049025-49-0

pharmaceutical intermediate

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pharmaceutical intermediate

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pharmaceutical intermediate

ReferenceSame Category

Diethylaminoethyl chloride hydrochloride

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pharmaceutical intermediate

ReferenceSame Category

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pharmaceutical intermediate

Related Reading

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2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Customs Tariff Classification

The international HS code for L-Phenylalanine, (alphaS)-alpha-((2-(4-morpholinyl)acetyl)amino)benzenebutanoyl-L-leucyl- (CAS 868540-16-3) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-2-[[(2S)-4-methyl-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acid

InChIKey

MIVQDKORYUSPTQ-QKDODKLFSA-N

SMILES

CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCC2=CC=CC=C2)NC(=O)CN3CCOCC3

Synonyms (12)
  • Carfilzomib Imputity 56
  • Carfilzomib intermediate-1

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