C49H76N6O11
925.2 g/mol
APIDanger
MC-MMAF
CAS863971-19-1
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material
MC-MMAF is a chemical compound functioning as an antibody-drug conjugate payload. It features a complex structure containing multiple amide bonds, an aromatic ring, and a maleimide group for conjugation.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Reading
Safety Reference
Danger
H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
Identifiers
IUPAC Name
(2S)-2-[[(2R,3R)-3-[(2S)-1-[(3R,4S,5S)-4-[[(2S)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoyl-methylamino]-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoyl]pyrrolidin-2-yl]-3-methoxy-2-methylpropanoyl]amino]-3-phenylpropanoic acid
InChIKey
ORFNVPGICPYLJV-YTVPMEHESA-N
SMILES
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN3C(=O)C=CC3=O
Synonyms (14)
- MC-MMAF
- Mafodotin (USAN)
- Mafodotin
- McMMAF (GMP)
- SGD-1269(MCMMAF)?
- mc-MMAF, mcMMAF, SGD-1269
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