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Home/Compounds/Pharmaceutical Intermediate/Ro-2433
C10H13FN2O5
260.22 g/mol
Pharmaceutical IntermediateWarning

(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine

CAS863329-66-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a fluorinated nucleoside derivative used as a pharmaceutical intermediate in the production of sofosbuvir. It contains two alcohol groups and a heterocyclic ring system.

Pharmaceutical intermediate for sofosbuvir synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione

InChIKey

ARKKGZQTGXJVKW-VPCXQMTMSA-N

SMILES

C[C@]1([C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O)F

Synonyms (21)
  • GS 331007
  • GS-331007 (PSI-6206)
  • PSI6206?
  • RO 2433;RO2433;RO-2433
  • Ro-2433