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Home/Compounds/Pharmaceutical Intermediate/(4aS,8aS,9S)-9-(Dimethylamino)-4a-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-8a,9-dihydro-3-(phenylmethoxy)-naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione
C26H34N2O5Si
482.6 g/mol
Pharmaceutical IntermediateWarning

(4aS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-4H,4aH,5H,8H,9H-naphtho(2,3-d)(1,2)oxazole-4,5-dione

CAS852821-06-8EC811-499-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a synthetic intermediate used in the platform-based synthesis of novel tetracycline antibiotics. It features a key chiral scaffold with protective silyl and benzyl ether groups, enabling further chemical modifications for antibiotic development.

Pharmaceutical intermediate for tetracycline antibiotic synthesisResearch compound for antibiotic development studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 852821-06-8

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name

(4aS,8aS,9S)-4a-[tert-butyl(dimethyl)silyl]oxy-9-(dimethylamino)-3-phenylmethoxy-8a,9-dihydro-8H-benzo[f][1,2]benzoxazole-4,5-dione

InChIKey

SLXLVVLJLQJWFG-JCWFFFCVSA-N

SMILES

CC(C)(C)[Si](C)(C)O[C@@]12[C@@H](CC=CC1=O)[C@@H](C3=C(C2=O)C(=NO3)OCC4=CC=CC=C4)N(C)C

Synonyms (7)
  • drsenone