C8H6FNO4
199.14 g/mol
Pharmaceutical IntermediateWarning
5-FLUORO-2-METHYL-3-NITROBENZOIC ACID
CAS850462-64-5EC822-496-5
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate
5-Fluoro-2-methyl-3-nitrobenzoic acid is a pharmaceutical intermediate used in the manufacturing of MEK inhibitors, including binimetinib. Binimetinib is a selective inhibitor of MEK, a central kinase in the tumor-promoting MAPK pathway, which has applications in oncology research.
Pharmaceutical intermediate for MEK inhibitor synthesisResearch compound for MAPK pathway studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 850462-64-5
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Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
5-fluoro-2-methyl-3-nitrobenzoic acid
InChIKey
CMZCBPLTJBYJHZ-UHFFFAOYSA-N
SMILES
CC1=C(C=C(C=C1[N+](=O)[O-])F)C(=O)O
Synonyms (3)
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