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Home/Compounds/Pharmaceutical Intermediate/Fmoc-L-Glutamic acid 1-tert-butyl ester
C24H27NO6
425.5 g/mol
Pharmaceutical IntermediateWarning

(4S)-5-(tert-butoxy)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopentanoic acid

CAS84793-07-7
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is an N-protected derivative of L-glutamic acid, featuring a fluorenylmethoxycarbonyl (Fmoc) group and a tert-butyl ester. It is primarily used as a building block in solid-phase peptide synthesis.

pharmaceutical intermediatereagent for peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.80

L-Fmoc-Aspartic acid alpha-tert-butyl ester

CAS129460-09-9

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SimilarStructure SimilarSimilarity 0.73

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ReferenceSame Category

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ReferenceSame Category

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ReferenceSame Category

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ReferenceSame Category

4-{[3-(4-acetylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one

CAS848136-41-4

pharmaceutical intermediate

Referencestereoisomer of

N-(9-Fluorenylmethyloxycarbonyl)-D-glutamic acid 1-tert-butyl ester

CAS109745-15-5

research compound

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

Read more

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid

InChIKey

GOPWHXPXSPIIQZ-FQEVSTJZSA-N

SMILES

CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Synonyms (16)
  • Fmoc-Glu-OtBu
  • Fmoc-L-Glu-OtBu

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