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Home/Compounds/Research Reagent/Trifluoromethyltrimethylsilane
C4H9F3Si
142.19 g/mol
Research ReagentDanger

(Trifluoromethyl)trimethylsilane

CAS81290-20-2
Category
Research Reagent
Compound Class
Organometallic
Primary Use
Research Compound

(Trifluoromethyl)trimethylsilane is an organosilicon compound widely employed as a trifluoromethylation reagent in organic synthesis. It serves as a convenient source of the trifluoromethyl group for introducing this moiety into various organic molecules, particularly in research and pharmaceutical intermediate manufacturing.

Trifluoromethylation reagent in organic synthesisBuilding block for pharmaceutical intermediates

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Flammable
Flammable
Harmful
Harmful
Danger
H225Highly flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

trimethyl(trifluoromethyl)silane

InChIKey

MWKJTNBSKNUMFN-UHFFFAOYSA-N

SMILES

C[Si](C)(C)C(F)(F)F

Synonyms (20)
  • TFMTMS
  • Ruppert's Reagent
  • Ruppert-Prakash Reagent
  • TMSCF(3)
  • trifluoromethyltrimetylsilane