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Home/Compounds/API/Cilastatin sodium
C16H25N2NaO5S
380.4 g/mol
APIWarning

Cilastatin sodium

CAS81129-83-1
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Cilastatin sodium is a pharmaceutical raw material used as a renal dehydropeptidase inhibitor. It is commonly combined with imipenem in antibiotic preparations to prevent the renal metabolism of imipenem, thereby enhancing its antibacterial activity.

pharmaceutical raw material for combination antibiotic productsrenal dehydropeptidase inhibitor in research and manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H319Causes serious eye irritation
Identifiers
IUPAC Name

sodium (Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoate

InChIKey

QXPBTTUOVWMPJN-QBNHLFMHSA-M

SMILES

CC1(C[C@@H]1C(=O)N/C(=C\CCCCSC[C@@H](C(=O)O)N)/C(=O)[O-])C.[Na+]

Synonyms (24)
  • Cilastatin sodium (JP17/USP)
  • CILASTATIN Na
  • Cilastatin Monosodium Salt
  • Cilastatin sodium
  • Cilastatin sodium CRS
  • Cilastatin sodium salt
  • Cilastatino
  • Monosodium Salt, Cilastatin
  • Salt, Cilastatin Monosodium
  • Sodium, Cilastatin