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Home/Compounds/API/Roxithromycin
C41H76N2O15
837 g/mol
APIWarning

Roxithromycin

CAS80214-83-1EC617-007-5
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Roxithromycin is a macrolide antibiotic compound used as an active pharmaceutical ingredient in the manufacture of medicinal products. It is a semisynthetic derivative of erythromycin, featuring a macrocyclic lactone ring with multiple hydroxyl and ether groups.

Pharmaceutical raw material for antibiotic productionCompound used in pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.89

PUBCHEM_71750076

CAS425365-66-8

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one

CAS111321-02-9

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

Erythromycin oxime

CAS13127-18-9

pharmaceutical raw material

ReferenceSame Category

Tamsulosin hydrochloride

CAS80223-99-0

pharmaceutical raw material

ReferenceSame Category

Spiramycin

CAS8025-81-8

pharmaceutical raw material

ReferenceSame Category

Ceftiofur

CAS80370-57-6

pharmaceutical raw material

ReferenceSame Category

Loxoprofen sodium

CAS80382-23-6

pharmaceutical raw material

Referencesame scaffold

PUBCHEM_71314812

CAS127182-44-9

pharmaceutical research compound

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Roxithromycin (CAS 80214-83-1) is 2941.50.

HS code (international, 6-digit)

2941.50

EU CN code (8-digit)

2941 50 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one

InChIKey

RXZBMPWDPOLZGW-XMRMVWPWSA-N

SMILES

CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

Synonyms (55)
  • Roxithromycin (JP18/USAN/INN)
  • (E)-roxithromycin
  • Abbotic;
  • Antibiotic RU 28965;
  • Azuril;
  • Cirumycin;
  • Infectoroxit
  • Macrosil;
  • ROXITHROMYCIN [MART.]
  • Rotramin;
  • Roxi-paed 1A Pharma
  • Roxithromycin CRS
  • Roxithromycine
  • Roxithromycine [French]
  • Roxithromycinum
  • Roxithromycinum [Latin]
  • Roxitrol;
  • Roxitromicina
  • Roxitromicina [Spanish]
  • Roxitromycin
  • Roxitromycine
  • Rulid
  • Rulide
  • Rulide (TN)
  • roxithromycin

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