C6H15ClOSi
166.72 g/mol
Research ReagentDanger
2-(Trimethylsilyl)ethoxymethyl chloride
CAS76513-69-4EC278-483-4
Category
Research Reagent
Compound Class
Halocarbon
Primary Use
Research Compound
2-(Trimethylsilyl)ethoxymethyl chloride (SEM-Cl) is an organochlorine compound used as a protecting reagent for hydroxyl groups. It allows selective protection and deprotection under mild conditions using fluoride in organic solvents, making it valuable in synthetic organic chemistry.
Protecting reagent for hydroxyl groups in organic synthesisDeprotection using fluoride under mild conditions
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 76513-69-4
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Safety Reference
Danger
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
Identifiers
IUPAC Name
2-(chloromethoxy)ethyl-trimethylsilane
InChIKey
BPXKZEMBEZGUAH-UHFFFAOYSA-N
SMILES
C[Si](C)(C)CCOCCl
Synonyms (32)
- SEM-Cl
- SEM-chloride