C12H9F3N2O2
270.21 g/mol
APIDanger
Leflunomide
CAS75706-12-6EC616-254-6
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Leflunomide is an immunosuppressive compound used as an active pharmaceutical ingredient in disease-modifying antirheumatic drug (DMARD) formulations. It functions by inhibiting dihydroorotate dehydrogenase, affecting pyrimidine synthesis.
pharmaceutical raw material for immunosuppressive formulationsactive pharmaceutical ingredient in DMARD manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
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CAS75708-92-8
pharmaceutical raw material
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pharmaceutical raw material
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pharmaceutical raw material
ReferenceSame Category
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CAS76-25-5
pharmaceutical raw material
Safety Reference
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Leflunomide (CAS 75706-12-6) is 2934.99.
HS code (international, 6-digit)
2934.99
EU CN code (8-digit)
2934 99 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
InChIKey
VHOGYURTWQBHIL-UHFFFAOYSA-N
SMILES
CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
Synonyms (42)
- SULOL
- Leflunomida [INN-Spanish]
- Leflunomide (JAN/USP/INN)
- Leflunomide for peak identification, European Pharmacopoeia (EP)
- Leflunomide, European Pharmacopoeia (EP)
- Leflunomide, United States Pharmacopeia (USP)
- Leflunomidum [INN-Latin]
- Lefunomide [Inn-Spanish]
- Arabloc
- Arava
- Arava (TN)
- LEFLUNOMIDE [MART.]
- Leflunomida
- Leflunomide (Standard)
- Leflunomide CRS
- Leflunomide ratiopharm
- Leflunomide teva
- Leflunomide winthrop
- Leflunomidum
- Repso
- SU 101 (pharmaceutical)
- leflunomide
- leflunomide medac
- lefunamide
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