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Home/Compounds/API/Leuprolide acetate
C61H88N16O14
1269.4 g/mol
APIDanger

Leuprolide acetate

CAS74381-53-6EC686-285-8
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Leuprolide acetate is a synthetic peptide compound used as an active pharmaceutical ingredient. It consists of a nonapeptide sequence in a salt-like form, characterized by a complex, highly flexible structure with multiple amide bonds and aromatic rings.

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Restricted or banned substances

Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.

Relevant lists:California Proposition 65

CAS 74381-53-6

Related Compounds

StrongSame Parent

Leuprolide

CAS53714-56-0

pharmaceutical raw material

StrongStructure SimilarSimilarity 1.00

Deslorelin

CAS57773-65-6

pharmaceutical raw material

ReferenceSame Category

Limaprost

CAS74397-12-9

pharmaceutical raw material

ReferenceSame Category

Benzobarbital

CAS744-80-9

pharmaceutical raw material

ReferenceSame Category

Alprostadil

CAS745-65-3

pharmaceutical raw material

ReferenceSame Category

Metadoxine

CAS74536-44-0

pharmaceutical raw material

Referencestereoisomer of

(des-gly10,d-leu6,d-leu7,pro-nhet9)-lhrh trifluoroacetate salt

CAS112710-58-4

pharmaceutical raw material

Referencestereoisomer of

(2S)-N-((2R)-1-(((2S)-1-(((2R)-1-(((2S)-1-(((2R)-1-(((2S)-1-(((2S)-5-(diaminomethylideneamino)-1-((2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-3-hydroxy-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)-5-oxopyrrolidine-2-carboxamide

CAS1872435-00-1

pharmaceutical raw material

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360May damage fertility or the unborn child
Regulatory Compliance1
  • California Proposition 65USRegulation
    Listed· listed since 1997-08-26Source

Customs Tariff Classification

The international HS code for Leuprolide acetate (CAS 74381-53-6) is 2937.19.

HS code (international, 6-digit)

2937.19

EU CN code (8-digit)

2937 19 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

InChIKey

RGLRXNKKBLIBQS-XNHQSDQCSA-N

SMILES

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6.CC(=O)O

Synonyms (67)
  • Abbott 43818
  • Acetate, Leuprolide
  • Carcinil
  • Depo-Eligard
  • Depo-Lupron
  • ELIGARD KIT
  • Eligard
  • Enanton
  • Enantone
  • Enantone-Gyn
  • Fensolvi
  • Fensolvi Kit
  • Ginecrin
  • LEUPRORELIN ACETATE [MART.]
  • LUPRON DEPOT-3
  • LUPRON DEPOT-4
  • LUPRON DEPOT-PED
  • LUTRATE DEPOT KIT
  • Leuplin
  • Leuplin depot
  • Leuporelin acetate
  • Leuprin
  • Leuprolide Monoacetate
  • Leuprolide acetate
  • Leuprolide acetate depot
  • Leuprolidine;
  • Leupron;
  • Leuprorelin acetate
  • Leuprorelin acetate salt
  • Lucrin
  • Lucrin Depot
  • Lupaneta
  • Lupron
  • Lupron Depot
  • Lupron Depot-3 Month
  • Lupron Depot-4 Month
  • Lupron Depot-Ped Kit
  • Lupron PED
  • Lutrate
  • Lutrate depot
  • Monoacetate, Leuprolide
  • Onectyl
  • Procren
  • Procren Depot
  • Procrin
  • Prostap
  • Trenantone
  • Uno-Enantone
  • Viadur