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Home/Compounds/Research Reagent/Hydroxyethylpiperazine ethane sulfonic acid
C8H18N2O4S
238.31 g/mol
Research Reagent

HEPES

CAS7365-45-9EC230-907-9
Category
Research Reagent
Compound Class
Other
Primary Use
Research Compound

HEPES is a zwitterionic sulfonic acid buffering agent and one of the twenty Good's buffers. It is widely used in cell culture for maintaining physiological pH, particularly under varying carbon dioxide concentrations.

cell culture bufferpH maintenance in biological research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.82

PIPES

CAS5625-37-6

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HEPPS

CAS16052-06-5

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SimilarStructure SimilarSimilarity 0.74

HEPBS

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Referencestereoisomer of

Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate

CAS75277-39-3

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Customs Tariff Classification

The international HS code for HEPES (CAS 7365-45-9) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

InChIKey

JKMHFZQWWAIEOD-UHFFFAOYSA-N

SMILES

C1CN(CCN1CCO)CCS(=O)(=O)O

Synonyms (45)
  • HEPES
  • 15(R)-hydroperoxy-EPE
  • 1d1p
  • 1dg9
  • HEPES buffered saline
  • HEPES solution
  • HEPES, >=99.0% (T)
  • HEPES, >=99.5% (titration)
  • HEPES, CellPUREtrade mark
  • HEPES, biochemical grade
  • HEPES, dry powder
  • HeBES
  • Monosodium Salt, HEPES
  • Salt, HEPES Monosodium
  • TVZ 7;WAS 13;NSC 166663

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