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Home/Compounds/Food Additive/L-histidine zwitterion
C6H9N3O2
155.15 g/mol
Food AdditiveWarning

L-histidine

CAS71-00-1EC200-745-3
Category
Food Additive
Compound Class
Natural Product
Primary Use
nutritional supplement and dietary additive

L-Histidine is an essential amino acid involved in protein biosynthesis, containing an imidazole side chain that gives it a positive charge at physiological pH. It is required for both infants and adults, as long-term studies have confirmed its essentiality throughout life.

nutritional supplementdietary additive

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

L-Histidine hydrochloride

CAS1007-42-7

essential amino acid supplement

StrongSame Parent

Histidine monohydrochloride monohydrate

CAS5934-29-2

pharmaceutical raw material

StrongSame Parent

Histidine monohydrochloride

CAS645-35-2

essential amino acid supplement

ApplicationSame Use

Tryptophan

CAS73-22-3

nutritional supplement and dietary additive

ApplicationSame Use

L-arginine

CAS74-79-3

nutritional supplement and dietary additive

ReferenceSame Category

Disodium glycyrrhizate

CAS71277-79-7

Food and cosmetic additive

ReferenceSame Category

Sodium lactate

CAS72-17-3

Food acidity regulator and preservative

ReferenceSame Category

L-valine zwitterion

CAS72-18-4

Nutritional supplement and dietary additive

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Customs Tariff Classification

The international HS code for L-histidine (CAS 71-00-1) is 2933.29.

HS code (international, 6-digit)

2933.29

EU CN code (8-digit)

2933 29 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid

InChIKey

HNDVDQJCIGZPNO-YFKPBYRVSA-N

SMILES

C1=C(NC=N1)C[C@@H](C(=O)O)N

Synonyms (76)
  • Histidina [INN-Spanish]
  • Histidine (USP/INN)
  • Histidine, European Pharmacopoeia (EP)
  • Histidinum [INN-Latin]
  • L-Histidine, United States Pharmacopeia (USP)
  • L-Histidine, cell culture tested, meets EP, USP testing specifications, from non-animal source
  • (S)1H-Imidazole-4-alanine
  • (s)-1h-imidazole-4-alanin
  • 1H-Imidazole-4-alanine, (S)-
  • 1hsl
  • 1lag
  • Anti-rheuma
  • H-His-OH
  • HISTIDINE [MART.]
  • HISTIDINE, L-
  • Histidine (L-Histidine)
  • Histidine (VAN)
  • Histidine (for injection)
  • Histidine CRS
  • Histidinum
  • Imidazole C-4(5) deriv. 5
  • Istidina
  • L-His
  • L-His-OH
  • L-Hisidine
  • L-Histidin
  • L-Histidine (H-His-OH)
  • L-Histidine (JP18)
  • L-Histidine (Standard)
  • L-Histidine 7409
  • L-Histidine High
  • L-Histidine High 7410
  • L-Histidine, p.a.
  • L-beta-(4-Imidazolyl)alanin
  • L-histidine
  • L-hystidine
  • L-isomer Histidine
  • MELOXICAM, HISTIDINE
  • S-Histidine
  • SERINE IMPURITY C
  • US9138393, Histidine
  • US9144538, Histidine
  • [3H]histidine
  • his
  • histidina
  • histidine

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