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Home/Compounds/Pharmaceutical Intermediate/(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid
C20H21NO4
339.4 g/mol
Pharmaceutical IntermediateWarning

Fmoc-L-valine

CAS68858-20-8
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Fmoc-L-valine is a derivative of the amino acid L-valine, protected with a fluorenylmethyloxycarbonyl (Fmoc) group at the N-terminus. It is widely employed as an intermediate in solid-phase peptide synthesis, enabling the stepwise construction of peptides.

Intermediate for peptide synthesisBuilding block in solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.80

(2S,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylpentanoic acid

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(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxybutanoic acid

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SimilarStructure SimilarSimilarity 0.80

Fmoc-D-allo-isoleucine

CAS118904-37-3

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SimilarStructure SimilarSimilarity 0.76

N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-L-alanine--water (1/1)

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ApplicationSame Use

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-alanine

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N-Benzyloxycarbonyl-D-aspartic acid

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Acetyl octapeptide-3

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Fmoc-Asp(OtBu)-Ser(Psi(Me,Me)pro)-OH

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Fmoc-L-valine (CAS 68858-20-8) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid

InChIKey

UGNIYGNGCNXHTR-SFHVURJKSA-N

SMILES

CC(C)[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Synonyms (21)
  • (s)-n-fmoc-valine
  • FMOC-VALINE
  • Fmoc-L-Val-OH
  • Fmoc-L-valine
  • Fmoc-Val-OH
  • Fmoc-Val-OH, >=98.0% (HPLC)
  • N-FMOC-VAL-OH
  • N-Fmoc-L-valine

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