C6H18N3OP
179.2 g/mol
Industrial ChemicalDanger
HMPA
CAS680-31-9EC211-653-8
Category
Industrial Chemical
Compound Class
Amide
Primary Use
solvent for organic synthesis
Hexamethylphosphoramide (HMPA) is a phosphoramide compound used as a solvent in organic synthesis. It is a colorless liquid that serves as a polar aprotic solvent for various chemical reactions.
solvent for organic synthesispolar aprotic solvent in chemical reactions
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Restricted or banned substances
Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.
Relevant lists:California Proposition 65
CAS 680-31-9
Related Compounds
ReferenceSame Category
2-Aminobenzenesulfonic acid (1-methylethylidene)di-4,1-phenylene ester
CAS68015-60-1
industrial chemical intermediate
ReferenceSame Category
Tetramethyl silicate
CAS681-84-5
Silicon compound for coatings and sealants
ReferenceSame Category
2,2-Difluoro-1,3-benzodioxole-5-acetonitrile
CAS68119-31-3
Fine chemical intermediate
ReferenceSame Category
4-Oxazolemethanol, 4-ethyl-2-(8-heptadecen-1-yl)-4,5-dihydro-
CAS68140-98-7
Viscosity modifier
Referencestereoisomer of
Tris(di(2H3)methylamido)phosphorus
CAS51219-90-0
research compound
Safety Reference
Danger
H340May cause genetic defects
H350May cause cancer
H303May be harmful if swallowed
H313May be harmful in contact with skin
H315Causes skin irritation
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
Regulatory Compliance1
- California Proposition 65USRegulation
Customs Tariff Classification
The international HS code for HMPA (CAS 680-31-9) is 2929.90.
HS code (international, 6-digit)
2929.90
EU CN code (8-digit)
2929 90 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
N-[bis(dimethylamino)phosphoryl]-N-methylmethanamine
InChIKey
GNOIPBMMFNIUFM-UHFFFAOYSA-N
SMILES
CN(C)P(=O)(N(C)C)N(C)C
Synonyms (52)
- HMPA
- HMPT
- HMPTA
- HPT
- ENT 50,882
- Eastman Inhibitor HPT
- Hempa
- Hexametapol
- Hexamethyl phosphoramide
- Hexamethylfosforamid
- Hexamethylfosforamid [Czech]
- Hexamethylphosphamide
- Hexamethylphosphoramid
- Hexamethylphosphoric triamide
- Hexamethylphosphorotriamide
- Hexamethylphosphotriamide
- Hexmethylphosphoramide
- Phosphoric hexamethyltriamide
- Phosphoryl hexamethyltriamide
- hexamethyiphosphoramide
- hexamethylphophoric triamide
- hexamethyltriamidophosphate
- hexarnethylphosphoramide
- phoric triamide, hexamethyl-