Home/Compounds/Pharmaceutical Intermediate/1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester
C12H11NO4
233.22 g/mol
Pharmaceutical IntermediateWarning
METHYL 1-ACETYL-2-OXO-3H-INDOLE-6-CARBOXYLATE
CAS676326-36-6EC857-183-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
Methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate is a chemical compound used as a pharmaceutical intermediate in the synthesis of nintedanib. It features a bicyclic indole core with acetyl, ester, and ketone functional groups.
Pharmaceutical intermediate for nintedanib synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 676326-36-6
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Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H341Suspected of causing genetic defects
Identifiers
IUPAC Name
methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate
InChIKey
QIMXPFXIAXDPBS-UHFFFAOYSA-N
SMILES
CC(=O)N1C(=O)CC2=C1C=C(C=C2)C(=O)OC
Synonyms (10)
- Nintedanib Impurity 4