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Home/Compounds/Pharmaceutical Intermediate/[(3R)-1-[7-(2-Butynyl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]carbamic acid 1,1-dimethylethyl ester
C30H36N8O4
572.7 g/mol
Pharmaceutical Intermediate

1,1-Dimethylethyl N-[(3R)-1-[7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]carbamate

CAS668273-75-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a Boc-protected pharmaceutical intermediate featuring a purine core linked to a piperidine ring and a quinazoline group. It is primarily used in the synthesis of more complex active pharmaceutical ingredients.

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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2-Chloro-5-methylnicotinic acid

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Referencesame scaffold

LINAGLIPTIN, (S)-

CAS668270-11-9

pharmaceutical raw material

Referencesame scaffold

Linagliptin

CAS668270-12-0

pharmaceutical raw material

Identifiers
IUPAC Name

tert-butyl N-[(3R)-1-[7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]piperidin-3-yl]carbamate

InChIKey

PQEIZFATTRGTNW-HXUWFJFHSA-N

SMILES

CC#CCN1C2=C(N=C1N3CCC[C@H](C3)NC(=O)OC(C)(C)C)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C

Synonyms (16)
  • Boc Linagliptin
  • Linagliptin Impurity 46
  • Linagliptin Impurity 66
  • Linagliptin N-Boc Impurity
  • N-Boc Linagliptin