C10H18ClN
187.71 g/mol
APIDanger
Amantadine hydrochloride
CAS665-66-7EC211-560-2
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Amantadine hydrochloride is an active pharmaceutical ingredient used in the manufacture of antiviral and antiparkinsonian medications. It is noted for potential developmental toxicity as indicated by certain regulatory labeling requirements.
Pharmaceutical raw material for influenza A virus infection managementPharmaceutical raw material for parkinsonism therapyPharmaceutical raw material for drug-induced extrapyramidal reaction treatment
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Restricted or banned substances
Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.
Relevant lists:California Proposition 65
CAS 665-66-7
Related Compounds
StrongSame Parent
Amantadine
CAS768-94-5
pharmaceutical raw material
ReferenceSame Category
(S)-baclofen
CAS66514-99-6
pharmaceutical raw material
ReferenceSame Category
Propacetamol hydrochloride
CAS66532-86-3
pharmaceutical raw material
ReferenceSame Category
Ansamitocin P-3
CAS66547-09-9
pharmaceutical raw material
ReferenceSame Category
Forskolin
CAS66575-29-9
pharmaceutical raw material
Referencestereoisomer of
Tricyclo[3.3.1.13,7]decan-2,2,8,8,9,9-d6-1-amine
CAS1219805-53-4
pharmaceutical raw material
Referencestereoisomer of
1-Adamantan-D15-amine
CAS33830-10-3
pharmaceutical intermediate
Safety Reference
Danger
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects
Regulatory Compliance1
- California Proposition 65USRegulation
Customs Tariff Classification
The international HS code for Amantadine hydrochloride (CAS 665-66-7) is 2921.30.
HS code (international, 6-digit)
2921.30
EU CN code (8-digit)
2921 30 99
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
adamantan-1-amine;hydrochloride
InChIKey
WOLHOYHSEKDWQH-UHFFFAOYSA-N
SMILES
C1C2CC3CC1CC(C2)(C3)N.Cl
Synonyms (59)
- Amantadine hydrochloride (JP18/USP)
- Amantadine hydrochloride, European Pharmacopoeia (EP)
- Amantadine hydrochloride, United States Pharmacopeia (USP)
- 1-Adamantylamine HCl
- 1-adamantylammonium chloride
- 665-66-7 (HCL)
- Adamantamine hydrochloride
- Adamantanamine hydrochloride
- Adamantine hydrochloride
- Adamantylamine hydrochloride
- Adamin
- Adamine
- Amantadine HCl
- Amantadine hydrochloride
- Amantadine hydrochloride CRS
- Amantan
- Amazolon
- Aminoadamantane hydrochloride
- Cerebramed
- EXP 105-1
- Gocovri (TN)
- Hofcomant
- Hydrochloride, Amantadine
- Influenol
- Lysovir
- Mantadan
- Mantadine
- Mantadix
- Midantan
- Midantane
- Mydantane
- Nurelin
- Osmolex
- Osmolex er
- Osmolex er (TN)
- Symadine
- Symmetrel
- Symmetrel (TN)
- Trivaline
- Virasol
- Virofral
- adamantanylamine, chloride