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Home/Compounds/Pharmaceutical Intermediate/2-Imino-9-(2,3,5-tri-O-benzoylpentofuranosyl)-3,9-dihydro-2H-purin-6-ol
C31H25N5O8
595.6 g/mol
Pharmaceutical Intermediate

2',3',5'-Tri-O-benzoyl Guanosine

CAS66048-53-1EC266-089-5
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

2',3',5'-Tri-O-benzoyl guanosine is a chemically modified nucleoside derivative used as a building block in the solid-phase synthesis of oligonucleotides. Its three benzoyl ester groups protect the ribose hydroxyls during chain elongation, enabling the controlled assembly of DNA or RNA sequences.

Building block in oligonucleotide synthesisIntermediate for pharmaceutical manufacturing of nucleic acid-based compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate

InChIKey

WZRBAVDJTYIQBI-VBHAUSMQSA-N

SMILES

C1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)OC(=O)C5=CC=CC=C5)OC(=O)C6=CC=CC=C6

Synonyms (8)

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