C10H24N4O4S
296.39 g/mol
APIWarning
Guanethidine monosulfate
CAS645-43-2EC211-442-0
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Guanethidine monosulfate is an antihypertensive active pharmaceutical ingredient that works by reducing the release of catecholamines such as norepinephrine. It is taken up by sympathetic nerve endings via the same transport mechanism as norepinephrine and accumulates in transmitter vesicles, where it displaces norepinephrine.
pharmaceutical raw material for antihypertensive drug manufacturingresearch compound for studying catecholamine release mechanisms
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Safety Reference
Warning
H302Harmful if swallowed
Customs Tariff Classification
The international HS code for Guanethidine monosulfate (CAS 645-43-2) is 2933.99.
HS code (international, 6-digit)
2933.99
EU CN code (8-digit)
2933 99 80
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
2-[2-(azocan-1-yl)ethyl]guanidine;sulfuric acid
InChIKey
YUFWAVFNITUSHI-UHFFFAOYSA-N
SMILES
C1CCCN(CCC1)CCN=C(N)N.OS(=O)(=O)O
Synonyms (38)
- Guanethidine monosulfate (USP)
- Guanethidine monosulfate, United States Pharmacopeia (USP)
- 645-43-2 (sulfate)
- Ganda
- Guanethidine (sulfate)
- Guanethidine Sulphae
- Guanethidine bisulfate
- Guanethidine monosulfate
- Guanethidine sulfate (JP17)
- Guanetidin sulfate
- Ismelin
- Ismelin (TN)
- Ismelin sulfate
- Ismeline
- Isobarin
- Isomelin
- Lotens
- Monosulfate, Guanethidine
- Octadin
- Octatensin
- guanethidine monosulphate
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