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Home/Compounds/Research Reagent/Hexahistidine
C36H44N18O7
840.9 g/mol
Research Reagent

Hexa-His

CAS64134-30-1
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound

Hexa-His is a peptide consisting of six histidine residues, commonly used as an affinity tag for protein purification. Its polyhistidine sequence enables strong binding to nickel or cobalt ions, facilitating the isolation of tagged recombinant proteins.

affinity tag for protein purification

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid

InChIKey

XSYUPRQVAHJETO-WPMUBMLPSA-N

SMILES

C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CC3=CN=CN3)C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](CC6=CN=CN6)C(=O)O)N

Synonyms (13)
  • 6xHis-tag
  • Hexa His tag
  • Hexa-His
  • His-tag
  • His6 tag
  • L-histidine hexapeptide
  • hexa histidine-tag

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