C7H7ClN4O5S2
326.7 g/mol
Pharmaceutical IntermediateWarning
4-Nitrosohydrochlorothiazide
CAS63779-86-2
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
4-Nitrosohydrochlorothiazide is a nitrosamine impurity standard used in pharmaceutical quality control. It is a derivative of hydrochlorothiazide and is structurally characterized as 6-chloro-4-nitroso-1,1-dioxo-2,3-dihydro-1λ6,2,4-benzothiadiazine-7-sulfonamide.
nitrosamine impurity standard for analytical testingreference compound in pharmaceutical impurity profiling
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 63779-86-2
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Referencesame scaffold
Hydrochlorothiazide
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pharmaceutical raw material
Referencesame scaffold
Altizide
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Safety Reference
Warning
H302Harmful if swallowed
H341Suspected of causing genetic defects
H351Suspected of causing cancer
Identifiers
IUPAC Name
6-chloro-4-nitroso-1,1-dioxo-2,3-dihydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide
InChIKey
QJNIRHJVSXLTEW-UHFFFAOYSA-N
SMILES
C1NS(=O)(=O)C2=CC(=C(C=C2N1N=O)Cl)S(=O)(=O)N
Synonyms (9)
- 4-Nitroso-hct
- 4-Nitrosohydrochlorothiazide
- N-Nitroso Hydrochlorothiazide