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Home/Compounds/API/(RS)-nisoldipine
C20H24N2O6
388.4 g/mol
APIWarning

Nisoldipine

CAS63675-72-9EC264-407-7
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Nisoldipine is a dihydropyridine compound that functions as a calcium channel blocker and is supplied as an active pharmaceutical ingredient. It is characterized by a 1,4-dihydropyridine core with methyl, methoxycarbonyl, o-nitrophenyl, and isobutoxycarbonyl substituents.

pharmaceutical raw material for antihypertensive formulationspharmaceutical raw material for antianginal formulations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.79

Nifedipine

CAS21829-25-4

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.73

Desisobutyl nisoldipine

CAS74936-71-3

pharmaceutical intermediate

ApplicationSame Use

Benidipine hydrochloride

CAS129262-07-3

pharmaceutical raw material

ApplicationSame Use

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl (3S)-1-(phenylmethyl)-3-piperidinyl ester, monohydrochloride, (4S)-

CAS129262-08-4

pharmaceutical raw material

ReferenceSame Category

Pramoxine hydrochloride

CAS637-58-1

pharmaceutical raw material

ReferenceSame Category

(9alpha,13alpha)-17-(Cyclobutylmethyl)-3-methoxymorphinan-14-ol

CAS63730-48-3

pharmaceutical raw material

ReferenceSame Category

Cyclosporin b

CAS63775-95-1

pharmaceutical raw material

ReferenceSame Category

Cyclosporin d

CAS63775-96-2

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Nisoldipine (CAS 63675-72-9) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

InChIKey

VKQFCGNPDRICFG-UHFFFAOYSA-N

SMILES

CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

Synonyms (45)
  • Nisoldipine (JAN/USAN/INN)
  • Nisoldipino [INN-Spanish]
  • Nisoldipinum [INN-Latin]
  • Bay k 5552
  • Baymycard
  • Baymycard, Norvasc, Syscor
  • Geomatrix 16e
  • NISOLDIPINE [MART.]
  • Nisocor
  • Nisoldipin
  • Nisoldipina
  • Nisoldipine (stn)
  • Nisoldipine SR
  • Nisoldipine, >=98% (HPLC)
  • Nisoldipine, ~97%
  • Nisoldipino
  • Nisoldipinum
  • Sular
  • Sular (TN)
  • Syscor
  • Syscor mr 10
  • Syscor mr 20
  • Syscor mr 30
  • US20230414632, Compound I-e
  • Zadipina
  • nisoldipine

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