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Home/Compounds/API/AST-487
C26H30F3N7O2
529.6 g/mol
API

AST 487

CAS630124-46-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

AST 487 is a chemical compound used as a RET kinase inhibitor in pharmaceutical research and manufacturing. It functions as a research compound for studying kinase-related pathways.

pharmaceutical raw materialresearch compound for kinase inhibition studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 630124-46-8

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Identifiers
IUPAC Name

1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea

InChIKey

ODPGGGTTYSGTGO-UHFFFAOYSA-N

SMILES

CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F

Synonyms (11)
  • AST-48
  • AST 487
  • AST-487 (NVP-AST487)
  • NVP-AST487