C11H21NO4
231.29 g/mol
Pharmaceutical IntermediateWarning
N-Boc-L-tert-Leucine
CAS62965-35-9EC613-118-8
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate
N-Boc-L-tert-Leucine is an amino acid derivative used as a building block in peptide synthesis. It features a tert-butyloxycarbonyl (Boc) protecting group, which is commonly employed to shield the amino group during solid-phase or solution-phase peptide assembly.
peptide synthesis intermediateresearch reagent for pharmaceutical manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 62965-35-9
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Referencestereoisomer of
N-Boc-D-tert-leucine
CAS124655-17-0
pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-3,3-dimethyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
InChIKey
LRFZIPCTFBPFLX-SSDOTTSWSA-N
SMILES
CC(C)(C)[C@@H](C(=O)O)NC(=O)OC(C)(C)C
Synonyms (33)
- BOC-L-TLE-OH
- BOC-TBU-GLYCINE
- Boc-L-alpha-t-butylglycine
- Boc-L-tert-leucine
- Boc-L-|A-tert-butylglycine
- Boc-Tle-OH
- Boc-Tle-OH, >=99.0% (T)
- Boc-tLeu-OH
- Boc-tert-Leucine
- N-Boc-L-tert-Leucine
- N-boc-t-leucine
- Nirmatrelvir Impurity 21