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Home/Compounds/Pharmaceutical Intermediate/2'-O-Methyl-5'-O-phosphonoadenylyl-(3'-->5')-guanosine
C21H28N10O14P2
706.5 g/mol
Pharmaceutical Intermediate

2'-O-Methyl-5'-O-phosphonoadenylyl-(3'-->5')-guanosine

CAS62828-60-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a modified dinucleotide phosphate, specifically a phosphorylated 2'-O-methyladenylyl-(3'->5')-guanosine, used as a pharmaceutical intermediate. It features a complex structure with multiple hydroxyl, amine, ether, and aromatic heterocyclic groups, indicating high polarity and suitability for research in nucleic acid chemistry.

Pharmaceutical intermediate for manufacturing modified oligonucleotidesResearch compound in nucleotide analog studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.89

Guanosine, 5′-O-phosphonoadenylyl-(3′→5′)-

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SimilarStructure SimilarSimilarity 0.80

PGpG

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SimilarStructure SimilarSimilarity 0.72

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Identifiers
IUPAC Name

[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-methoxy-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate

InChIKey

XQBFQZRTNDQTOK-XPWFQUROSA-N

SMILES

CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C5N=C(NC6=O)N)O)O

Synonyms (5)
  • (2'OMe-5'P-A)pG, TEA salt
  • PAPG DIMER