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Home/Compounds/API/Riociguat
C20H19FN8O2
422.4 g/mol
APIWarning

Riociguat

CAS625115-55-1
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Riociguat is a stimulator of soluble guanylyl cyclase (sGC), used as an active pharmaceutical ingredient in the manufacturing of medications for pulmonary hypertension. It is the first drug in its class and is primarily indicated for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.

pharmaceutical raw material for pulmonary hypertension therapiesactive ingredient in sGC stimulator-class medications

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Pholcodine monohydrate

CAS6254-99-5

pharmaceutical raw material

ReferenceSame Category

(+)-Cloprostenol sodium

CAS62561-03-9

pharmaceutical raw material

ReferenceSame Category

Emideltide

CAS62568-57-4

pharmaceutical raw material

ReferenceSame Category

Captopril

CAS62571-86-2

pharmaceutical raw material

Referencesame scaffold

Vericiguat

CAS1350653-20-1

pharmaceutical raw material

Referencesame scaffold

2-(5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine

CAS1350653-30-3

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed

Customs Tariff Classification

The international HS code for Riociguat (CAS 625115-55-1) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate

InChIKey

WXXSNCNJFUAIDG-UHFFFAOYSA-N

SMILES

CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC

Synonyms (24)
  • GZO
  • Riociguat (JAN/USAN/INN)
  • Adempas
  • Adempas (TN)
  • BAY 63-2521
  • BAY 63-2521; BAY 632521
  • Riociguat
  • Riociguat (BAY 63-2521)
  • Riociguat (Standard)
  • Riociguat CRS
  • Riociguate
  • riociguatum

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