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Home/Compounds/Research Reagent/3'-deoxythymidine 5'-triphosphate
C10H17N2O13P3
466.17 g/mol
Research Reagent

DdTTP

CAS611-60-9
Category
Research Reagent
Compound Class
Heterocycle
Primary Use
Research Compound

ddTTP is a modified nucleotide used as a chain-terminating inhibitor in DNA sequencing. It is a thymidine analog that lacks hydroxyl groups at both the 2' and 3' positions of the ribose ring, preventing further DNA chain elongation upon incorporation.

Research reagent for DNA sequencingChain-terminating nucleotide in Sanger sequencing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Referencestereoisomer of

Sodium;[hydroxy-[hydroxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl]oxyphosphoryl] hydrogen phosphate

CAS128524-26-5

research compound

Identifiers
IUPAC Name

[hydroxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate

InChIKey

URGJWIFLBWJRMF-JGVFFNPUSA-N

SMILES

CC1=CN(C(=O)NC1=O)[C@H]2CC[C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O

Synonyms (16)
  • (free acid)
  • 2',3'-DDTTP
  • 2',3'-DIDEOXY TTP
  • Dideoxy-ttp
  • ddTTP