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Home/Compounds/API/Cyclosporine
C62H111N11O12
1202.6 g/mol
APIDanger

Cyclosporin A

CAS59865-13-3EC611-907-1
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Cyclosporin A is a cyclic peptide compound produced by the fungus Tolypocladium inflatum. It is an active pharmaceutical ingredient primarily used as an immunosuppressant, acting mainly against T-lymphocytes to inhibit cell-mediated immunity.

Organ transplantationControl of immune-mediated dermatological diseases in veterinary use

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.96

Cyclosporin e

CAS63798-73-2

research compound

StrongStructure SimilarSimilarity 0.89

Cyclosporin b

CAS63775-95-1

pharmaceutical raw material

StrongStructure SimilarSimilarity 0.89

Cyclosporin d

CAS63775-96-2

pharmaceutical raw material

ReferenceSame Category

Benoxinate hydrochloride

CAS5987-82-6

pharmaceutical raw material

ReferenceSame Category

Glabridin

CAS59870-68-7

pharmaceutical raw material

ReferenceSame Category

Sulfasalazine

CAS599-79-1

pharmaceutical raw material

ReferenceSame Category

Zinc citrate dihydrate

CAS5990-32-9

pharmaceutical raw material

Referencestereoisomer of

Cyclosporine

CAS79217-60-0

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H302Harmful if swallowed
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H362May cause harm to breast-fed children
H370Causes damage to organs
Identifiers
IUPAC Name

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

InChIKey

PMATZTZNYRCHOR-CGLBZJNRSA-N

SMILES

CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

Synonyms (121)
  • CEQUA
  • CSA
  • CYA
  • VEVYE
  • Ciclosporin for system suitability, European Pharmacopoeia (EP)
  • Ciclosporin, European Pharmacopoeia (EP)
  • Ciclosporina [INN-Spanish]
  • Ciclosporine [INN-French]
  • Ciclosporinum [INN-Latin]
  • Cyclosporine, United States Pharmacopeia (USP)
  • ,32-undecaone
  • 1c5f
  • 1cyn
  • 2wfj
  • 2z6w
  • 4jjm
  • ANTIBIOTIC S-7481F1
  • Abrammune
  • Arpimune ME
  • Atopica
  • Atopica for Cats
  • CB-01-09 MMX
  • CICLOSPORIN [MART.]
  • Capimune
  • Capsorin
  • CicloMulsion
  • Cicloral (antibiotic)
  • Ciclosporin
  • Ciclosporin CRS
  • Ciclosporin DT
  • Ciclosporina
  • Ciclosporina Germed
  • Ciclosporine
  • Ciclosporinum
  • Cipol N
  • Consupren
  • Consupren S
  • CsA & IFN.alpha.
  • CsANeoral
  • CyA NOF
  • Cyclavance
  • CycloSPORINE, Modfied
  • Cyclokat
  • Cyclorin;
  • Cyclosporin
  • Cyclosporin A & IFN.alpha.
  • Cyclosporin A (Standard)
  • Cyclosporin A, >=98.5% (TLC)
  • Cyclosporin A, VETRANAL(TM)
  • Cyclosporine A
  • Cyclosporine Modified
  • Cyclosporine manufacturer
  • Cyclosporine microemulsion
  • Cyclosporine/Chondroitin PF
  • Cyclosporine;Ciclosporin
  • Deximune
  • Equoral
  • Gengraf
  • Ikervis
  • Imusporin
  • Mitogard
  • Modulis for Cats
  • Modulis for Dogs
  • Modusik-A
  • Neoplanta
  • Neoral
  • NeuroSTAT
  • OL 27-400
  • Optimmune
  • Optimmune Ophthalmic
  • Papilock
  • Papilock Mini
  • Pulminiq
  • Ramihyphin A
  • Restasis
  • Restasis MultiDose
  • S 7481F1
  • S-Neoral
  • SDZ-OXL 400
  • Sandimmun
  • Sandimmun Neoral
  • Sandimmune
  • Sandimmune Neoral
  • Sang 35
  • SangCyA
  • Seciera
  • Sigmasporin
  • Sigmasporin Microoral
  • Sporimune
  • Vanquoral
  • Vekacia
  • Zinograf ME
  • Zyclorin
  • cyclosporin A
  • cyclosporine