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Home/Compounds/API/8-Chloro-6-(2-fluorophenyl)-1-methyl-5-oxo-4H-5λ⁵-imidazo[1,5-a][1,4]benzodiazepine
C18H13ClFN3O
341.8 g/mol
API

Midazolam 5-Oxide

CAS59468-83-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Midazolam 5-Oxide is an N-oxide derivative of the benzodiazepine midazolam, characterized by an oxidized nitrogen atom in the imidazo-benzodiazepine ring system. It is primarily recognized as a process-related impurity encountered during the manufacture of midazolam active pharmaceutical ingredient.

reference standard for midazolam impurity testingquality control marker in pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

1-hydroxymidazolam

CAS59468-90-5

pharmaceutical raw material

ReferenceSame Category

Ethyl 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

CAS59469-49-7

pharmaceutical raw material

ReferenceSame Category

Midazolam 6H-

CAS59469-74-8

pharmaceutical raw material

ReferenceSame Category

Somatostatin, tyr(11)-

CAS59481-27-5

pharmaceutical raw material

Referencesame scaffold

3-Carboxy-2-[8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-2-ium-2-yl]propanoate

CAS2531288-23-8

pharmaceutical intermediate

Identifiers
IUPAC Name

8-chloro-6-(2-fluorophenyl)-1-methyl-5-oxido-4H-imidazo[1,5-a][1,4]benzodiazepin-5-ium

InChIKey

FIDBLKWFRFIVLJ-UHFFFAOYSA-N

SMILES

CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=[N+](C2)[O-])C4=CC=CC=C4F

Synonyms (10)
  • 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide; Midazolam 5-Oxide; Midazolam Imp. D (EP)
  • Midazolam EP Impurity D
  • Midazolam 5-Oxide
  • Midazolam impurity D
  • Midazolam oxide