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Home/Compounds/API/Midazolam
C16H15ClFN3
303.76 g/mol
API

7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1h-1,4-benzodiazepine-2-methanamine

CAS59467-64-0
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

This compound is a benzodiazepine derivative used as an active pharmaceutical ingredient in the manufacture of pharmaceutical products. It is characterized by a structure containing amine and halogen functional groups within a three-ring aromatic system.

Pharmaceutical raw material for midazolam-related impuritiesReference standard for analytical testing in pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

2-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine Dimaleate

CAS59469-29-3

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.72

Desfluoro-aminodimaleate Midazolam Impurity;

CAS138729-69-8

pharmaceutical intermediate

ReferenceSame Category

8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine

CAS59467-69-5

pharmaceutical raw material

ReferenceSame Category

Midazolam

CAS59467-70-8

pharmaceutical raw material

ReferenceSame Category

Midazolam EP Impurity G

CAS59467-86-6

pharmaceutical raw material

ReferenceSame Category

Midazolam hydrochloride

CAS59467-96-8

pharmaceutical raw material

Customs Tariff Classification

The international HS code for 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1h-1,4-benzodiazepine-2-methanamine (CAS 59467-64-0) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

[7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine

InChIKey

LSQOUBKWMBDIPL-UHFFFAOYSA-N

SMILES

C1C(NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CN

Synonyms (11)
  • Midazolam Imp. E (EP); 1H-1,4-Benzodiazepine-2-methanamine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-; [(2RS)-7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine; Midazolam Impurity E
  • Midazolam amino compound
  • Midazolam impurity E

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