C17H22N2O3
302.37 g/mol
Research ReagentWarning
Trichostatin A
CAS58880-19-6EC611-758-2
Category
Research Reagent
Compound Class
Natural Product
Primary Use
Research Compound
Trichostatin A is a hydroxamic acid antibiotic antifungal agent produced by Streptomyces species, known for its role as a histone deacetylase inhibitor tool compound. It chelates the zinc ion in the active site of histone deacetylases, thereby modulating chromatin structure and gene expression.
histone deacetylase inhibitor tool compoundgeroprotector researchbacterial metabolite
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 58880-19-6
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Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
InChIKey
RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES
C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Synonyms (35)
- 3C10
- A-300-I
- TSA
- TSN
- VTR297
- (R)-Trichostatin A
- 1c3r
- 3f0r
- 58880-19-6 (R-isomer)
- Antibiotic A-300
- SGCTO-002
- TSA antibioitc
- Trichlostatin A
- Trichostatin
- Trichostatin A (TSA)
- Trichostatin(s)
- Tricostatin A
- trichostatin A
- trichostatine a