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Home/Compounds/Pharmaceutical Intermediate/O-tert-Butyl-L-threonine tert-butyl ester acetate salt
C14H29NO5
291.38 g/mol
Pharmaceutical Intermediate

(2S,3R)-tert-Butyl 2-amino-3-(tert-butoxy)butanoate acetate

CAS5854-77-3EC227-464-9
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid intermediate, specifically the tert-butyl ester and O-tert-butyl ether derivative of L-threonine, presented as an acetic acid salt. It is primarily used in peptide synthesis as a building block for introducing threonine residues with protected side chains.

Peptide synthesis intermediateProtected amino acid for solid-phase or solution-phase synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

acetic acid;tert-butyl (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoate

InChIKey

BGAUVMFJRASONL-RJUBDTSPSA-N

SMILES

C[C@H]([C@@H](C(=O)OC(C)(C)C)N)OC(C)(C)C.CC(=O)O

Synonyms (16)
  • H-THR(TBU)-OTBU ACOH