C17H21ClN2S
320.9 g/mol
APIDanger
PROMETHAZINE HYDROCHLORIDE
CAS58-33-3EC200-375-2
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Promethazine hydrochloride is a salt form of promethazine, a first-generation antihistamine used as an active pharmaceutical ingredient. It is commonly employed as a sedative and antiemetic in pharmaceutical manufacturing.
active pharmaceutical ingredient for antihistamine formulationssedative agent in pharmaceutical preparationsantiemetic compound for manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 58-33-3
Related Compounds
StrongSame Parent
Promethazine teoclate
CAS17693-51-5
pharmaceutical raw material
ReferenceSame Category
Tetrabenazine
CAS58-46-8
pharmaceutical raw material
ReferenceSame Category
Ethacrynic acid
CAS58-54-8
pharmaceutical raw material
ReferenceSame Category
Theophylline
CAS58-55-9
pharmaceutical raw material
ReferenceSame Category
Pyridoxine hydrochloride
CAS58-56-0
pharmaceutical raw material
Referencestereoisomer of
N,N-Dimethyl-1-[(1,3,7,9-²H₄)-10H-phenothiazin-10-yl]propan-2-amine—hydrogen chloride (1/1)
CAS1173018-74-0
research compound
Referencesame scaffold
N-nitroso-desmethyl-promethazine
CAS94511-44-1
pharmaceutical intermediate
Referencesame scaffold
Trimeprazine tartrate
CAS4330-99-8
pharmaceutical raw material
Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
InChIKey
XXPDBLUZJRXNNZ-UHFFFAOYSA-N
SMILES
CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl
Synonyms (101)
- PRONASE
- Promethazine for peak identification, European Pharmacopoeia (EP)
- Promethazine hydrochloride (JP18/USP)
- Promethazine hydrochloride, European Pharmacopoeia (EP)
- Promethazine hydrochloride, United States Pharmacopeia (USP)
- 3277 R.P.
- 58-33-3 (HCl)
- Allerfen
- Anergan
- Anergan 25
- Anergan 50
- Avomine
- Bonnox
- Closin
- Diprasine
- Diprazin
- Dorme
- Duplamin
- Eusedon Mono
- Fellozine
- Fenergan
- Frinova
- Ganphen
- Genphen
- Goodnight
- Hibechin
- Histantil
- Kinetosin
- Lergigan
- Mymethazine Fortis
- PHENERGAN PLAIN
- PMS Promethazine
- PROMETHAZINE HYDROCHLORIDE
- PROMETHAZINI HYDROCHLORIDUM
- Phanergan D
- Phenadoz
- Phencen
- Phenergan
- Phenergan (TN)
- Phenergan Fortis
- Phenergan hydrochloride
- Phenergan nightime
- Phenhalal
- Pipolfen
- Pipolphen
- Plletia
- Primine
- Promantine
- Prome
- Prometh Fortis
- Prometh Plain
- Promethacon
- Promethazine HCI
- Promethazine Hcl
- Promethazine Plain
- Promethazine chloride
- Promethazine hydrochlorine
- Promethegan
- Promethegan (TN)
- Promethiazin
- Promethiazin [German]
- Proneurin
- Prorex
- Pyrethia
- Q-mazine
- Remsed
- Romergan
- Sarantihist
- Soporil
- V-Gan
- component of Mepergan