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Home/Compounds/Pharmaceutical Intermediate/Menadione
C11H8O2
172.18 g/mol
Pharmaceutical IntermediateWarning

Menadione

CAS58-27-5EC200-372-6
Category
Pharmaceutical Intermediate
Compound Class
Aromatic
Primary Use
Pharmaceutical Intermediate

Menadione is a synthetic naphthoquinone derivative with the physiologic properties of vitamin K. It is primarily used as an intermediate in the industrial synthesis of phylloquinone (vitamin K1).

Intermediate in phylloquinone productionVeterinary antidote to bishydroxycoumarin poisoning (including sweet clover poisoning)

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Uridine

CAS58-96-8

pharmaceutical intermediate

ReferenceSame Category

Quinolin-6-ol

CAS580-16-5

pharmaceutical intermediate

ReferenceSame Category

4-Oxocyclohexaneacetic acid ethyl ester

CAS58012-34-3

pharmaceutical intermediate

ReferenceSame Category

Methyl 2,4-dihydroxy-6-pentylbenzoate

CAS58016-28-7

pharmaceutical intermediate

Referencestereoisomer of

Menadione-d8

CAS478171-80-1

research compound

Referencestereoisomer of

2-(Methyl-D3)-1,4-naphthoquinone

CAS5172-16-7

research compound

Referencesame scaffold

2-chloro-1,4-naphthoquinone

CAS1010-60-2

pharmaceutical intermediate

Referencesame scaffold

1,4-naphthoquinone-d6

CAS26473-08-5

research compound

Safety Reference

Harmful
Harmful
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Menadione (CAS 58-27-5) is 2914.69.

HS code (international, 6-digit)

2914.69

EU CN code (8-digit)

2914 69 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-methylnaphthalene-1,4-dione

InChIKey

MJVAVZPDRWSRRC-UHFFFAOYSA-N

SMILES

CC1=CC(=O)C2=CC=CC=C2C1=O

Synonyms (91)
  • MNQ
  • Menadione (USP)
  • Menadione, European Pharmacopoeia (EP)
  • Menadione, United States Pharmacopeia (USP)
  • Menadione, meets USP testing specifications
  • Phytomenadione Imp. A (EP); Menadione; 2-methylnaphthalene-1,4-dione; Phytomenadione Impurity A
  • 1,4-Naphthoquinone, 2-methyl-
  • 2-Methyl-1,4-naftochinon
  • 2-Methyl-1,4-naphthalendione
  • 2-Methyl-1,4-naphthalenedione
  • 2-Methyl-1,4-naphthochinon
  • 2-Methyl-1,4-naphthodione
  • 2-Methyl-1,4-naphthoquinone
  • 2-Methylnaphthoquinone
  • 2-methyl-1,4-napthoquinone
  • 2-methylnaphthalene-1,4-dione
  • 3-Methyl-1,4-naphthoquinone
  • 3-methyl-1,4-naphthalenedione
  • Aquakay
  • Aquinone
  • Bisulfite, Menadione
  • Bisulfite, Menadione Sodium
  • Hemodal
  • Juva-K
  • K-Thrombyl
  • K-Vitan
  • Kaergona
  • Kanone
  • Kappaxan
  • Kappaxan (VAN)
  • Kappaxin
  • Kappaxin (TN)
  • Karcon
  • Kareon
  • Kativ-G
  • Kayklot
  • Kaykot
  • Kaynone
  • Kayquinone
  • Kipca
  • Klottone
  • Koaxin
  • Kolklot
  • MENADIONE [MART.]
  • Memodol
  • Menadion
  • Menadione (K3)
  • Menadione (Standard)
  • Menadione (Vitamin K3)
  • Menadione 1528
  • Menadione CRS
  • Menadione Phenolic
  • Menadione semiquinone
  • Menadione, 9
  • Menadione, crystalline
  • Menadionum
  • Menaphthene
  • Menaphthon
  • Menaphthone
  • Menaphtone
  • Menaquinone 0
  • Menaquinone O
  • Mendione
  • Methyl-1,4-naphthalenedione
  • Methyl-1,4-naphthoquinone
  • Mitenon
  • Mitenone
  • PHYTOMENADIONE IMPURITY A
  • Panosine
  • Prokayvit
  • Sodium Bisulfite, Menadione
  • Synkay
  • Thyloquinone
  • Usaf ek-5185
  • Vitamin K0
  • Vitamin K2(0)
  • Vitamin K3
  • enadione (1.05793)
  • menadione

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