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Home/Compounds/Pharmaceutical Intermediate/Tert-Butyl 4-{6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl}piperazine-1-carboxylate
C27H34BrN7O3
584.5 g/mol
Pharmaceutical Intermediate

Tert-Butyl 4-[6-(6-Bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylate

CAS571188-82-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a brominated pyridopyrimidine derivative with a tert-butyl piperazine carboxylate substituent. It is primarily significant as a key pharmaceutical intermediate used in the manufacturing of Palbociclib.

Pharmaceutical intermediate for Palbociclib synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.72

Tert-Butyl 4-[6-[[6-(1-Butoxyethenyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-yl]amino]-pyridin-3-yl]-piperazine-1-carboxylate

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pharmaceutical intermediate

ReferenceSame Category

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester

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pharmaceutical intermediate

ReferenceSame Category

5-(4-Methylpiperazin-1-yl)pyridin-2-amine

CAS571189-49-6

pharmaceutical intermediate

ReferenceSame Category

N-(4-Amino-3-methoxyphenyl)methanesulfonamide

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pharmaceutical intermediate

ReferenceSame Category

Ethyl 2-(triphenylphosphoranylidene)propionate

CAS5717-37-3

pharmaceutical intermediate

Referencesame scaffold

N-Nitroso Palbociclib 1

CAS2955712-44-2

nitrosamine impurity standard

Referencesame scaffold

Palbociclib

CAS571190-30-2

pharmaceutical raw material

Referencesame scaffold

Palbociclib hydrochloride

CAS827022-32-2

pharmaceutical raw material

Identifiers
IUPAC Name

tert-butyl 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]piperazine-1-carboxylate

InChIKey

UTSOLZWQDXJQRH-UHFFFAOYSA-N

SMILES

CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)C(=O)OC(C)(C)C)C5CCCC5)Br

Synonyms (10)
  • Palbociclib Impurity 23