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Home/Compounds/API/Avatrombopag
C29H34Cl2N6O3S2
649.7 g/mol
API

1-[3-chloro-5-[[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-yl]carbamoyl]pyridin-2-yl]piperidine-4-carboxylic acid

CAS570406-98-3
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Avatrombopag is a small-molecule thrombopoietin receptor agonist that increases platelet counts. It is a pharmaceutical raw material used in the manufacturing of oral formulations for patients with thrombocytopenia associated with chronic liver disease.

pharmaceutical raw material for platelet-increasing oral formulationscompound for use in chronic liver disease-associated thrombocytopenia

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Avatrombopag maleate

CAS677007-74-8

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

Ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate

CAS570403-14-4

research compound

ApplicationSame Use

Lusutrombopag

CAS1110766-97-6

pharmaceutical raw material

ApplicationSame Use

Eltrombopag Amide

CAS1246929-02-1

pharmaceutical raw material

ApplicationSame Use

Eltrombopag olamine

CAS496775-62-3

pharmaceutical raw material

ReferenceSame Category

Desflurane

CAS57041-67-5

pharmaceutical raw material

ReferenceSame Category

6-Ketoestradiol

CAS571-92-6

pharmaceutical raw material

ReferenceSame Category

4-[(4-Methyl-4-oxo-4λ⁵-piperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide

CAS571186-91-9

pharmaceutical raw material

Identifiers
IUPAC Name

1-[3-chloro-5-[[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-yl]carbamoyl]-2-pyridinyl]piperidine-4-carboxylic acid

InChIKey

OFZJKCQENFPZBH-UHFFFAOYSA-N

SMILES

C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl

Synonyms (18)
  • E-5501
  • Avatrombopag (USAN/INN)
  • 570406-98-3 (free base)
  • AKR-501;E5501;YM477
  • Avatrombopag
  • Avatrombopag (AKR-501)
  • Avatrombopag (Standard)
  • Avatrombopag free base
  • Doptelet
  • E5501 compound
  • E5501;AKR-501;YM477
  • avatrombopagum