C8H6FNO
151.14 g/mol
Research ReagentDanger
5-fluoro-1,3-dihydroindol-2-one
CAS56341-41-4EC638-803-9
Category
Research Reagent
Compound Class
Amide
Primary Use
Research Compound
5-Fluoro-1,3-dihydroindol-2-one is a research compound belonging to the class of VEGFR-2 (kinase insert domain receptor) inhibitors. These synthetic molecules bind competitively to the ATP site of the tyrosine kinase domain, potentially interfering with signaling pathways involved in tumor proliferation, metastasis, and angiogenesis.
laboratory research as a VEGFR-2 inhibitorresearch tool for studying angiogenesis and lymphangiogenesis pathwayscompound for anticancer research involving tyrosine kinase inhibition
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 56341-41-4
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Safety Reference
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
5-fluoro-1,3-dihydroindol-2-one
InChIKey
DDIIYGHHUMKDGI-UHFFFAOYSA-N
SMILES
C1C2=C(C=CC(=C2)F)NC1=O
Synonyms (19)
- 5-FLUOROINDOLE-2-ONE
- 5-Fluoro-2-indolinone
- 5-Fluoro-2-oxindole
- 5-Fluoro-2-oxoindoline
- 5-Fluorooxindole
- 5-fluoroindolin-2-one
- 5-fluoroindolinone
- Oxindole derivative
- Sunitinib Impurity F
- Sunitinib Intermediate