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Home/Compounds/Research Reagent/5-Fluoro-2-oxindole
C8H6FNO
151.14 g/mol
Research ReagentDanger

5-fluoro-1,3-dihydroindol-2-one

CAS56341-41-4EC638-803-9
Category
Research Reagent
Compound Class
Amide
Primary Use
Research Compound

5-Fluoro-1,3-dihydroindol-2-one is a research compound belonging to the class of VEGFR-2 (kinase insert domain receptor) inhibitors. These synthetic molecules bind competitively to the ATP site of the tyrosine kinase domain, potentially interfering with signaling pathways involved in tumor proliferation, metastasis, and angiogenesis.

laboratory research as a VEGFR-2 inhibitorresearch tool for studying angiogenesis and lymphangiogenesis pathwayscompound for anticancer research involving tyrosine kinase inhibition

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.72

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5,6-Difluoro-2-oxoindole

CAS71294-07-0

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Referencesame scaffold

Oxindole

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research compound

Safety Reference

Toxic
Toxic
Harmful
Harmful
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for 5-fluoro-1,3-dihydroindol-2-one (CAS 56341-41-4) is 2933.79.

HS code (international, 6-digit)

2933.79

EU CN code (8-digit)

2933 79 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

5-fluoro-1,3-dihydroindol-2-one

InChIKey

DDIIYGHHUMKDGI-UHFFFAOYSA-N

SMILES

C1C2=C(C=CC(=C2)F)NC1=O

Synonyms (19)
  • 5-FLUOROINDOLE-2-ONE
  • 5-Fluoro-2-indolinone
  • 5-Fluoro-2-oxindole
  • 5-Fluoro-2-oxoindoline
  • 5-Fluorooxindole
  • 5-fluoroindolin-2-one
  • 5-fluoroindolinone
  • Oxindole derivative
  • Sunitinib Impurity F
  • Sunitinib Intermediate

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