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Home/Compounds/Pharmaceutical Intermediate/Isobutyl chlorocarbonate
C5H9ClO2
136.58 g/mol
Pharmaceutical IntermediateDanger

Isobutyl chloroformate

CAS543-27-1EC208-840-1
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

Isobutyl chloroformate is a colorless to light-colored liquid that is insoluble in water and denser than water. It is highly corrosive to skin, eyes, and mucous membranes, and is very toxic by ingestion, inhalation, and skin absorption.

Peptide reagentChemical intermediate in pharmaceutical manufacturingLaboratory reagent for organic synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Sodium 4-chloro-1-hydroxybutanesulfonate

CAS54322-20-2

pharmaceutical intermediate

ReferenceSame Category

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CAS54323-50-1

pharmaceutical intermediate

ReferenceSame Category

4-Aminophthalic acid

CAS5434-21-9

pharmaceutical intermediate

ReferenceSame Category

4-Hydroxy-3-nitropyridine

CAS5435-54-1

pharmaceutical intermediate

Safety Reference

Flammable
Flammable
Corrosive
Corrosive
Toxic
Toxic
Harmful
Harmful
Danger
H226Flammable liquid and vapour
H290May be corrosive to metals
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H331Toxic if inhaled
H335May cause respiratory irritation
Regulatory Compliance1
  • CN Catalogue of Hazardous ChemicalsCNRegulation
    Listed· listed since 2015-05-01Source

Customs Tariff Classification

The international HS code for Isobutyl chloroformate (CAS 543-27-1) is 2915.90.

HS code (international, 6-digit)

2915.90

EU CN code (8-digit)

2915 90 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-methylpropyl carbonochloridate

InChIKey

YOETUEMZNOLGDB-UHFFFAOYSA-N

SMILES

CC(C)COC(=O)Cl

Synonyms (29)
  • IBCF
  • 2-Methylpropyl chloroformate
  • ClCO2iBu
  • ClCOOi-Bu
  • Isobutyl chloridocarbonate
  • Isobutyl chlorocarbonate
  • Isobutyl chloroformate
  • Octreotide Impurity 67
  • i-Butyl chloroformate
  • iBuOCOCl
  • isobutlychloroformate
  • isobutyichioroformate
  • isobutyl carbonochloridate
  • isobutyl chioroformate
  • isobutyl chloroformat
  • isobutylchlorformate
  • isobutylchoroformate
  • isobutyloxycarbonyl chloride

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