C11H18ClNO
215.72 g/mol
APIWarning
Mexiletine hydrochloride
CAS5370-01-4EC226-362-1
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Mexiletine hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. It acts by inhibiting the inward sodium current in cardiac cells, slowing nerve impulses in the heart and stabilizing the heartbeat.
Antiarrhythmic agent (Class IB) for pharmaceutical manufacturingLocal anesthetic for pharmaceutical useActive pharmaceutical ingredient in drug formulations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 5370-01-4
Related Compounds
StrongSame Parent
(RS)-mexiletine
CAS31828-71-4
pharmaceutical raw material
ReferenceSame Category
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Referencestereoisomer of
(S)-1-(2,6-Dimethylphenoxy)propan-2-amine hydrochloride
CAS81771-85-9
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
Identifiers
IUPAC Name
1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride
InChIKey
NFEIBWMZVIVJLQ-UHFFFAOYSA-N
SMILES
CC1=C(C(=CC=C1)C)OCC(C)N.Cl
Synonyms (37)
- Mexiletine hydrochloride (JP18/USP)
- Mexiletine hydrochloride, European Pharmacopoeia (EP)
- Mexiletine hydrochloride, United States Pharmacopeia (USP)
- KOE-1173 (hydrochloride)
- Katen
- Ko 1173 Cl
- MEXILITENE HYDROCHLORIDE
- Mexiletene hydrochloride
- Mexiletine HCL
- Mexiletine hydrochloride
- Mexiletine hydrochloride CRS
- Mexitil
- Mexitil (TN)
- Mexitil p.l.