C11H18ClNO
215.72 g/mol
APIWarning
Mexiletine hydrochloride
CAS5370-01-4EC226-362-1
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Mexiletine hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. It acts by inhibiting the inward sodium current in cardiac cells, slowing nerve impulses in the heart and stabilizing the heartbeat.
Antiarrhythmic agent (Class IB) for pharmaceutical manufacturingLocal anesthetic for pharmaceutical useActive pharmaceutical ingredient in drug formulations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
(RS)-mexiletine
CAS31828-71-4
pharmaceutical raw material
ReferenceSame Category
Leuprolide
CAS53714-56-0
pharmaceutical raw material
ReferenceSame Category
Carprofen
CAS53716-49-7
pharmaceutical raw material
ReferenceSame Category
Oxfendazole
CAS53716-50-0
pharmaceutical raw material
ReferenceSame Category
11-keto oxcarbazepine
CAS537693-29-1
pharmaceutical raw material
Referencestereoisomer of
(S)-1-(2,6-Dimethylphenoxy)propan-2-amine hydrochloride
CAS81771-85-9
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
Customs Tariff Classification
The international HS code for Mexiletine hydrochloride (CAS 5370-01-4) is 2922.19.
HS code (international, 6-digit)
2922.19
EU CN code (8-digit)
2922 19 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride
InChIKey
NFEIBWMZVIVJLQ-UHFFFAOYSA-N
SMILES
CC1=C(C(=CC=C1)C)OCC(C)N.Cl
Synonyms (37)
- Mexiletine hydrochloride (JP18/USP)
- Mexiletine hydrochloride, European Pharmacopoeia (EP)
- Mexiletine hydrochloride, United States Pharmacopeia (USP)
- KOE-1173 (hydrochloride)
- Katen
- Ko 1173 Cl
- MEXILITENE HYDROCHLORIDE
- Mexiletene hydrochloride
- Mexiletine HCL
- Mexiletine hydrochloride
- Mexiletine hydrochloride CRS
- Mexitil
- Mexitil (TN)
- Mexitil p.l.
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