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Home/Compounds/API/Sirolimus
C51H79NO13
914.2 g/mol
APIDanger

Rapamycin

CAS53123-88-9
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material

Rapamycin is a triene macrolide antibiotic produced by Streptomyces hygroscopicus. It is primarily used as an immunosuppressant pharmaceutical raw material in research and manufacturing, particularly for preventing organ transplant rejection.

Immunosuppressant research compoundLaboratory reagent for immunochemistryPharmaceutical raw material for transplant rejection prevention

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.87

Everolimus

CAS159351-69-6

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.84

Temsirolimus

CAS162635-04-3

pharmaceutical raw material

ApplicationSame Use

Cyclosporin d

CAS63775-96-2

pharmaceutical raw material

ReferenceSame Category

Acemetacin

CAS53164-05-9

pharmaceutical raw material

ReferenceSame Category

Sisomicin sulfate

CAS53179-09-2

pharmaceutical raw material

ReferenceSame Category

Loperamide

CAS53179-11-6

pharmaceutical raw material

ReferenceSame Category

Pirfenidone

CAS53179-13-8

pharmaceutical raw material

Referencestereoisomer of

Sirolimus Impurity 2

CAS157182-37-1

Pharmaceutical impurity reference standard

Safety Reference

Health Hazard
Health Hazard
Danger
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Customs Tariff Classification

The international HS code for Rapamycin (CAS 53123-88-9) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

InChIKey

QFJCIRLUMZQUOT-HPLJOQBZSA-N

SMILES

C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC

Synonyms (62)
  • A-275
  • FYARRO
  • HYFTOR
  • RAP
  • RAPA
  • RPM
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34 aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hex adecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydro xy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy- 6,8,12,14,20,26-hexamethyl-23,27-ep
  • 1fkb
  • 1pbk
  • AY 22 989
  • Antibiotic AY 22989
  • Cypher
  • EVEROLIMUS IMPURITY A
  • Human Blood - Sirolimus
  • I 2190A
  • LCP-Siro
  • Perceiva
  • Rapammune
  • Rapamune
  • Rapamycin (>85%)
  • Rapamycin (GMP Like)
  • Rapamycin (GMP)
  • Rapamycin (Sirolimus)
  • Rapamycin (Standard)
  • Rapamycin - Bio-X trade mark
  • Rapamycin, VETRANAL(TM)
  • Rapamycin,Sirolimus,Rapamune
  • SIIA 9268A
  • SILA 9268A
  • SIROLIMUS COMPONENT OF SM-88
  • SIROLIMUS [MART.]
  • SM-88 COMPONENT SIROLIMUS
  • Sirolimus
  • Supralimus
  • Wy 090217
  • rapalimus
  • rapamycin
  • sirolimusum
  • traene-2,3,10,14,20-pentone

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