C19H16ClNO4
357.8 g/mol
APIDanger
Indomethacin
CAS53-86-1EC200-186-5
Category
API
Compound Class
Organic Acid
Primary Use
Pharmaceutical Raw Material
Indomethacin is an active pharmaceutical ingredient. It is a nonsteroidal anti-inflammatory compound that functions as a cyclooxygenase inhibitor and is used in pharmaceutical manufacturing and formulation.
pharmaceutical raw materialnon-steroidal anti-inflammatory drug substancecyclooxygenase inhibitor compound
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.81
Acemetacin
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pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.78
Carboxymethyl acemetacin
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pharmaceutical intermediate
ReferenceSame Category
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pharmaceutical raw material
ReferenceSame Category
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CAS530-78-9
pharmaceutical raw material
ReferenceSame Category
Alitretinoin
CAS5300-03-8
pharmaceutical raw material
ReferenceSame Category
Norelgestromin
CAS53016-31-2
pharmaceutical raw material
Referencesame scaffold
2-tert-Butoxy-2-oxoethyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate
CAS75302-98-6
pharmaceutical intermediate
Referencesame scaffold
2-[2-[1-(4-chloro-2,3,5,6-tetradeuteriobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid
CAS1196151-16-2
pharmaceutical raw material
Safety Reference
Danger
H300Fatal if swallowed
H301Toxic if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
Customs Tariff Classification
The international HS code for Indomethacin (CAS 53-86-1) is 2933.99.
HS code (international, 6-digit)
2933.99
EU CN code (8-digit)
2933 99 80
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
InChIKey
CGIGDMFJXJATDK-UHFFFAOYSA-N
SMILES
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
Synonyms (160)
- FLAM
- IMN
- USAN
- Indometacin (JP18/INN)
- Indometacin; Acemetacin EP Impurity B
- Indometacina [INN-Spanish]
- Indometacine [INN-French]
- Indometacinum [INN-Latin]
- Indomethacin (USP)
- Indomethacin, European Pharmacopoeia (EP)
- Indomethacin, United States Pharmacopeia (USP)
- Indomethacin, meets USP testing specifications
- 1z9h
- 4kyk
- ACEMETACIN IMPURITY B
- Aconip
- Aconip (TN)
- Amuno
- Arthrexin
- Artracin
- Artracin sr
- Artrinovo
- Artrivia
- Berlind 75 ret
- Bonidin
- Bonidon
- Bonidon Gel
- Catlep
- Chibro-amuno
- Chrono-indicid
- Chrono-indocid
- Confortid
- Dolcidium
- Dolcidium PL
- Dolovin
- Durametacin
- Elmetacin
- Flexin continus
- Flexin-25 continus
- Flexin-50 continus
- Flexin-75 continus
- Flexin;
- Hicin
- INDOMETACIN [MART.]
- Idomethine
- Imbrilon
- Inacid
- Indacin
- Indameth
- Indmethacine
- Indo-Lemmon
- Indo-Spray
- Indo-paed
- Indo-phlogont
- Indo-rectolmin
- Indo-tablinen
- Indochron E-R
- Indocid
- Indocid (pharmaceutical)
- Indocid ret
- Indocid-r
- Indocin
- Indocin (TN)
- Indocin Sr
- Indocollyre
- Indoderm
- Indoflex
- Indolar
- Indolar SR
- Indomax-75 sr
- Indomecol
- Indomed
- Indomee
- Indomet 140
- Indometacin (Indomethacin)
- Indometacin CRS
- Indometacina
- Indometacine
- Indometacinum
- Indometacyna
- Indometacyna [Polish]
- Indomethacin & MAP-30
- Indomethacin (GMP)
- Indomethacin (Standard)
- Indomethacin ER
- Indomethacin Extended-release
- Indomethacin, >=99% (TLC)
- Indomethacine
- Indomethacinum
- Indomethancin
- Indomethazine
- Indomethine
- Indometicina
- Indometicina [Spanish]
- Indomo
- Indomod
- Indonol
- Indoptic
- Indoptol
- Indorektal
- Indotard mr 75
- Indoxen
- Inflazon
- Infrocin
- Innamit
- Inteban
- Inteban sp
- Lausit
- Ledmecin
- Maximet sr
- Metacen
- Metartril
- Methazine
- Metindol
- Mezolin
- Miametan
- Mikametan
- Mobilan
- Osmosin
- Pardelprin mr
- Reumacide
- Rheumacin LA
- Rimacid
- Sadoreum
- Slo-indo
- Tannex
- Tivorbex
- Vonum
- indometacin
- indomethacin
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