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Home/Compounds/Pharmaceutical Intermediate/Z-THR(TBU)-OME
C17H25NO5
323.4 g/mol
Pharmaceutical Intermediate

Z-THR(TBU)-OME

CAS52785-41-8
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Z-THR(TBU)-OME (This compound) is a protected amino acid derivative commonly used as a building block in peptide synthesis. It features a benzyloxycarbonyl (Cbz) amino protecting group and a tert-butyl ether side-chain protection on the threonine residue, making it suitable for stepwise solid-phase or solution-phase peptide assembly.

Protected amino acid building block for peptide synthesisIntermediate in pharmaceutical manufacturing of peptide-based compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

methyl (2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoate

InChIKey

NKWFWFWEJCKORD-OCCSQVGLSA-N

SMILES

C[C@H]([C@@H](C(=O)OC)NC(=O)OCC1=CC=CC=C1)OC(C)(C)C

Synonyms (5)
  • Linaclotide Impurity 23
  • Z-THR(TBU)-OME