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Home/Compounds/API/Hydroxyproline
C5H9NO3
131.13 g/mol
APIWarning

L-Hydroxyproline

CAS51-35-4EC200-091-9
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material

L-Hydroxyproline is a non-essential amino acid that serves as a key component of collagen, the primary structural protein in connective tissues. It is endogenously produced in the human body and participates in metabolic and catabolic processes.

Pharmaceutical raw material for collagen-related manufacturingResearch compound for metabolic and catabolic studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

(2S,4R)-4-hydroxypyrrolidine-2-carboxylic Acid Hydrochloride

CAS32968-78-8

pharmaceutical intermediate

ReferenceSame Category

Norepinephrine bitartrate

CAS51-40-1

pharmaceutical raw material

ReferenceSame Category

Norepinephrine

CAS51-41-2

pharmaceutical raw material

ReferenceSame Category

Epinephrine bitartrate

CAS51-42-3

pharmaceutical raw material

ReferenceSame Category

Epinephrine

CAS51-43-4

pharmaceutical raw material

Referencestereoisomer of

Cis-4-hydroxyproline

CAS618-27-9

Non-essential amino acid analog

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for L-Hydroxyproline (CAS 51-35-4) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid

InChIKey

PMMYEEVYMWASQN-DMTCNVIQSA-N

SMILES

C1[C@H](CN[C@@H]1C(=O)O)O

Synonyms (54)
  • (2S,4R)-4-hydroxyproline
  • (2s,4r)-4-hydroxy-l-proline
  • (4R)-4-hydroxy-L-proline
  • (4r)-hydroxyproline
  • 4 HYDROXYPROLINE
  • 4-Hydroxy-L-proline
  • 4-L-Hydroxyproline
  • H-Hyp-OH
  • H-trans-Hyp-OH
  • Hydroxyproline (VAN)
  • Hydroxyproline,(l)
  • Hyp
  • Hypro
  • L-4-hydroxyproline
  • L-4-transhydroxyproline
  • L-Hydroxyproline
  • L-Hydroxyproline (Standard)
  • L-Hydroxyproline pure
  • L-Proline, 4-hydroxy-
  • L-Proline, 4-hydroxy-, (4R)-
  • L-Proline, 4-hydroxy-, trans-
  • L-Proline, trans-
  • L-threo-4-hydroxyproline
  • L-trans-4-hydroxy-proline
  • Ls-Hydroxyproline
  • NMH-Pro
  • Proline, 4-hydroxy-
  • Proline, 4-hydroxy- (VAN)
  • Proline, 4-hydroxy-, L-
  • cis 4 Hydroxyproline
  • delta-Hydroxyproline
  • hydroxiproline
  • hydroxy-L-proline
  • hydroxyproline
  • oxyproline
  • trans 4-hydroxy-l-proline
  • trans-Hydroxyproline
  • trans-L-Hydroxyproline

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