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Home/Compounds/API/Terfenadine
C32H41NO2
471.7 g/mol
API

Terfenadine

CAS50679-08-8EC256-710-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Terfenadine is a pharmaceutical raw material that was formerly used as an antihistamine for allergic conditions. It was withdrawn from most global markets due to a risk of cardiac arrhythmias and has been largely superseded by its active metabolite fexofenadine.

antihistamine active pharmaceutical ingredientpharmaceutical raw material for allergy research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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(2S)-4-amino-N-[(1S,2R,3R,4S,5R)-5-amino-4-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

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Safety Reference

Environmental Hazard
Environmental Hazard
H413May cause long lasting harmful effects to aquatic life

Customs Tariff Classification

The international HS code for Terfenadine (CAS 50679-08-8) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol

InChIKey

GUGOEEXESWIERI-UHFFFAOYSA-N

SMILES

CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O

Synonyms (55)
  • Terfenadina [INN-Spanish]
  • Terfenadine (JAN/USAN/INN)
  • Terfenadine, European Pharmacopoeia (EP)
  • Terfenadine, United States Pharmacopeia (USP)
  • Terfenadinum [INN-Latin]
  • Aldaban
  • Allerplus
  • Cyater
  • Heparinsodium
  • Histafen
  • Histafen 120
  • Nebralin
  • Seldane
  • Seldane (TN)
  • TERFENADINE [MART.]
  • Teldane
  • Teldanex
  • Terdin
  • Terfen
  • Terfenadin
  • Terfenadin Ratiopharm
  • Terfenadina
  • Terfenadine (Standard)
  • Terfenadine CRS
  • Terfenadinum
  • Terfenidine
  • Terfenor
  • Terfenor fte
  • Terfex
  • Terfinax 120
  • Terfinax 60
  • Ternadin
  • Triludan
  • Triludan fte
  • teraenadine
  • terfenadine

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