C32H41NO2
471.7 g/mol
API
Terfenadine
CAS50679-08-8EC256-710-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Terfenadine is a pharmaceutical raw material that was formerly used as an antihistamine for allergic conditions. It was withdrawn from most global markets due to a risk of cardiac arrhythmias and has been largely superseded by its active metabolite fexofenadine.
antihistamine active pharmaceutical ingredientpharmaceutical raw material for allergy research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 50679-08-8
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(2S)-4-amino-N-[(1S,2R,3R,4S,5R)-5-amino-4-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
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Safety Reference
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name
1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
InChIKey
GUGOEEXESWIERI-UHFFFAOYSA-N
SMILES
CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O
Synonyms (55)
- Terfenadina [INN-Spanish]
- Terfenadine (JAN/USAN/INN)
- Terfenadine, European Pharmacopoeia (EP)
- Terfenadine, United States Pharmacopeia (USP)
- Terfenadinum [INN-Latin]
- Aldaban
- Allerplus
- Cyater
- Heparinsodium
- Histafen
- Histafen 120
- Nebralin
- Seldane
- Seldane (TN)
- TERFENADINE [MART.]
- Teldane
- Teldanex
- Terdin
- Terfen
- Terfenadin
- Terfenadin Ratiopharm
- Terfenadina
- Terfenadine (Standard)
- Terfenadine CRS
- Terfenadinum
- Terfenidine
- Terfenor
- Terfenor fte
- Terfex
- Terfinax 120
- Terfinax 60
- Ternadin
- Triludan
- Triludan fte
- teraenadine
- terfenadine