C22H18N6
366.4 g/mol
APIWarning
Rilpivirine
CAS500287-72-9
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Rilpivirine is a pharmaceutical raw material used as an HIV-1 non-nucleoside reverse transcriptase inhibitor. It is a second-generation NNRTI with improved potency and a longer half-life.
HIV-1 non-nucleoside reverse transcriptase inhibitor for pharmaceutical manufacturingAntiretroviral compound for drug formulation
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H319Causes serious eye irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Customs Tariff Classification
The international HS code for Rilpivirine (CAS 500287-72-9) is 2933.59.
HS code (international, 6-digit)
2933.59
EU CN code (8-digit)
2933 59 95
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile
InChIKey
YIBOMRUWOWDFLG-ONEGZZNKSA-N
SMILES
CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
Synonyms (28)
- T27
- Rilpivirine (JAN/USAN/INN)
- 278, TMC
- 500287-72-9 (free base)
- Edurant(TM)
- HCl, Rilpivirine
- Hydrochloride, Rilpivirine
- R278474;TMC278
- RILPIVIRINE [MART.]
- Rekambys (TN)
- Rilpivirina
- Rilpivirine
- Rilpivirine Z-Isomer HCl
- Rilpivirine free base
- rilpivirinum
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